Biomarkers, Immune Monitoring and Drug Discovery
Biomarkers, Immune Monitoring and Drug Discovery
Clinical Investigator Collaborative
Principal Investigators Paul O'Byrne & Gail Gauvreau, McMaster University; Louis-Philippe Boulet, Université Laval; Don Cockcroft, University of Saskatchewan; Mark Fitzgerald, University of British Columbia; and Irvin Mayers, University of Alberta
Biomarkers: Intracellular Cytokine Production
Principal Investigator Bruce Mazer, McGill University
Development of an adaptive immune phenotyping platform for identification of biomarkers correlating with the development of allergic disease and clinical efficacy following therapeutic intervention
Principal Investigator Mark Larché, McMaster UniversityOntogeny and genetic polymorphisms of the innate immune system intersecting in atopy
Principal Investigators Tobias Kollmann, University of British Columbia,
and Stuart Turvey, University of British ColumbiaHemopoietic stem cells as biomarkers of atopy, airways inflammation, and sources of 'epigenetic' memory (formerly Progenitors in atopy development)
Principal Investigator Judah Denburg, McMaster UniversityNon-invasive diagnostics: Metabolics for the various phenotypes of asthma (formerly Diagnosing the various phenotypes of asthma: The use of urine NMR)
Principal Investigator Darryl Adamko, University of Alberta
Regulation of lung mucosal immune responses by heterologous exposure to multiple infectious and allergic agents
Principal Investigator Manel Jordana, McMaster University
Environmental impact on the epithelial immune barrier in asthma
Principal Investigator Tony Bai, University of British Columbia
Role of mast cells and eosinophils in allergic inflammation and fibrosis of the lung
Principal Investigator Kelly McNagny, University of British Columbia
Study of the pathogenesis and reversibility of airway damage and repair during chronic mucosal immune responses to environmental allergies
Principal Investigator Jean-Pierre Lavoie, Université de Montréal